Prevention of laboratory animal allergy

IN-DEPTH REVIEW Prevention of laboratory animal allergy

Laboratory animal allergy (LAA) is a common health problem in pharmaceutical research workers. The aetiology of LAA is well established and it is generally accepted that approximately one-third of exposed people may develop symptoms of LAA—see review articles [1,2]. The most common symptoms are rhinitis, conjunctivitis and contact urticaria; ~10% of workers may experience the most serious sympt...

Laboratory animal allergy: an update.

Allergic reactions are among the most common conditions affecting the health of workers involved in the care and use of research animals. Between 11 and 44% of the individuals working with laboratory animals report work-related allergic symptoms. Of those who become symptomatic, 4 to 22% may eventually develop occupational asthma that can persist even after exposure ceases. Allergic symptoms co...

Mechanism and epidemiology of laboratory animal allergy.

Laboratory animal allergy (LAA) is a form of occupational allergic disease. The development of laboratory animal allergy is due to the presence of IgE antibodies directed against animal proteins. The process of sensitization (development of IgE antibodies) is a complex process which involves interaction of antigen presenting cells and lymphocytes of the Th-2 cell type. These cells generate a ho...

Prevalence of Laboratory Animal Allergy in Laboratory Workers Tae

Using Airshowers to Decrease Laboratory Animal Allergy

The use of wet showers when entering an animal facility, especially barrier units, has been common practice for many years. The shower reinforces required changes of attire and removes skin microorganisms and allergens, thereby preventing infections inside the animal facility and the spread of allergens outside. Laboratory animal allergy is indeed one of the most common occupational health haza...